Spectrally encoded confocal scanning laser ophthalmoscopy.
نویسندگان
چکیده
We present in vivo human fundus imaging using a fiber-based confocal scanning laser ophthalmoscope (SLO). Spectrally encoded confocal scanning laser ophthalmoscopy (SECSLO) utilizes a spectral encoding technique in one dimension, combined with single-axis lateral scanning, to create video-rate reflectivity maps of the fundus. This implementation of the SLO allows for high-contrast high-resolution in vivo human retinal imaging through a single-mode optical fiber. We experimentally quantify the full confocality of SECSLO in both the spectrally encoded and laterally scanned dimensions, and demonstrate 50 Hz frame rate fundus imaging.
منابع مشابه
Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography
Scanning laser ophthalmoscopy (SLO) and spectral domain optical coherence tomography (SDOCT) have become essential clinical diagnostic tools in ophthalmology by allowing for video-rate noninvasive en face and depth-resolved visualization of retinal structure. Current generation multimodal imaging systems that combine both SLO and OCT as a means of image tracking remain complex in their hardware...
متن کاملConfocal scanning laser ophthalmoscopy in glaucoma diagnosis and management
The early diagnosis and detection of progression are two key-elements in the actual management of glaucoma. The current opinion in clinical practice is to quantify the structural damage for a better follow-up of the patient and the standardization of the results. The present review is a concise survey of literature covering the period of 1990-2010, documenting the evidence-based role of confoca...
متن کاملConfocal scanning laser ophthalmoscopy improvement by use of Mueller-matrix polarimetry.
A new technique for improving the signal-to-noise ratio and the contrast in images recorded with a confocal scanning laser system is presented. The method is based on the incorporation of a polarimeter into the setup. After the spatially resolved Mueller matrix of a sample was calculated, images for incident light with different states of polarization were reconstructed, and both the best and t...
متن کاملSimultaneous SD-OCT and Confocal SLO-Imaging
optical coherence tomography (OCT) can be correlated with findings on confocal scanning laser ophthalmoscopy (cSLO) imaging, including fluoresceinand ICGangiography, fundus autofluorescence (FAF) – or reflectance images, in exact topographic correspondance. Simultaneous acquisition is time-efficient and facilitates correlation of findings in the different imaging modalities. Eye tracking allows...
متن کاملHigh resolution fundus imaging by confocal scanning laser ophthalmoscopy in the mouse
We evaluated fundus imaging using a modified confocal scanning laser ophthalmoscope (cSLO) in mice. Examinations were performed in conscious, untrained mice. The largest field of view measured 1,520 x 1,520 mu, with a significant interindividual variability, itself correlated to biometric variability. The composite field of view extended up to the ora serrata. The reflectance imaging associated...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Optics letters
دوره 35 4 شماره
صفحات -
تاریخ انتشار 2010